![]() ![]() (2020) presented a graphical illustration of the impact of mechanical deadspace on V Alv for different settings that provided the same minute ventilation (V E ) considering a male, 175 cm tall and 150 mL/kg PBW/min. breaths per minute Alveolar ventilation equals 12 × (500 - 150), or 4200 ml/min. We also know that the conditions associated with ARDS may increase deadspace, again, lowering V Alv. The following are commonly used general formulas: Alveolar gas equation: pA O2 150 - pa CO2/0.8 Minute ventilation tidal volume x respiratory rate (normal is 4-6 L/min) Tidal volume alveolar space + dead space Anion gap Na+ - (Cl- + HCO3 ) (normal is 12 ± 2) Delta-delta (anion gap - 12) / (24 - HCO3) Osmolal gap measured. Phase II (mixture of dead space + alveolar gas). These numbers do not take into account any other mechanical deadspace that may be included such as end-tidal monitoring, any additional connectors, catheter mounts, etc. If this patient was ventilated with 4 mL/kg, the deadspace ratio would further increase and lower V Alv. PBW – 79.9 kg (round to 80 for math sake)Īnatomical deadspace (V Danat ) – 1 mL/lb PBW or 176 mL ![]()
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